Featured in this issue is an editorial on Zambia’s rising cancer burden, which calls for stronger early detection, improved diagnosis and treatment, sustainable financing, robust surveillance, and patient-centred care. Also featured are outbreak investigations on anthrax at the wildlife–human interface in Mosi-oa-Tunya National Park and scabies in a school in Lusangazi District, as well as a Quarter 1, 2026 surveillance summary of priority diseases and events.